Description

(S)-2-Fluoropropionic Acid CAS NO 57965-29-4 is a high-value, chiral fluorinated organic acid serving as a critical building block in advanced chemical synthesis. Its importance lies in the unique reactivity and stereochemistry imparted by the fluorine atom and the (S)-configuration, enabling the development of novel compounds with enhanced properties. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for drug discovery, active ingredient development, and material science applications.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides and pesticides, where the specific stereochemistry can influence biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine-Containing Material Science: Building block for specialty polymers, liquid crystals, and electronic materials where fluorine incorporation modifies stability and performance.
• Bioconjugation and Probe Synthesis: Useful for introducing a fluorinated, carboxylic acid handle into biomolecules or fluorescent probes for research and diagnostics.
• Custom Synthesis and R&D: A versatile starting material for contract research organizations (CROs) and academic labs exploring new fluorination methodologies and chiral compound libraries.

Basic Information

Product Name	(S)-2-Fluoropropionic Acid
CAS No.	57965-29-4
Molecular Formula	C₃H₅FO₂
Molecular Weight	92.07 g/mol
Synonyms	(S)-(-)-2-Fluoropropionic Acid; (S)-α-Fluoropropionic Acid; (2S)-2-Fluoropropanoic Acid; L-2-Fluoropropionic Acid; (S)-2-Fluoropropanoic Acid; FA 2S; (S)-2-FPA
EINECS	Contact for details

Quality Control

Our (S)-2-Fluoropropionic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent, store separately from bases, oxidizing agents, and incompatible materials. Use appropriate corrosion-resistant containers.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.