Description

2-Hydroxycyclopentane-1-Carbonitrile is a versatile chiral building block and key synthetic intermediate in organic chemistry. Its value lies in the functional group combination of a hydroxyl and a nitrile, which allows for diverse chemical transformations and the construction of complex molecular architectures. This compound is particularly needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopentane or pyrrolidine rings.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its nitrile functionality.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent in organic synthesis laboratories for methodological development and constructing complex natural product analogs.
• Ligand and Catalyst Development: The hydroxyl and nitrile groups make it a candidate for developing novel chiral ligands and organocatalysts.

Basic Information

Product Name	2-Hydroxycyclopentane-1-Carbonitrile
CAS No.	57836-12-1
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	2-Hydroxycyclopentanecarbonitrile; 1-Cyano-2-hydroxycyclopentane; 2-Hydroxy-1-cyclopentanecarbonitrile; trans-2-Hydroxycyclopentane-1-carbonitrile; cis-2-Hydroxycyclopentane-1-carbonitrile; Cyclopentanecarbonitrile, 2-hydroxy-; 2-Hydroxycyclopentyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Hydroxycyclopentane-1-Carbonitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomer specific)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.