Description

4-(2,6-Dichloroisonicotinoyl)Morpholine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct morpholine-substituted nicotinamide structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its specific substitution pattern enables precise molecular modifications. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides with targeted action.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the production chain of specific, high-value APIs requiring its unique dichloroisonicotinoyl moiety.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-(2,6-Dichloroisonicotinoyl)Morpholine
CAS No.	57803-44-8
Molecular Formula	C10H10Cl2N2O2
Molecular Weight	261.10 g/mol
Synonyms	Morpholine, 4-[(2,6-dichloro-4-pyridinyl)carbonyl]-; 4-(2,6-Dichloropyridine-4-carbonyl)morpholine; 2,6-Dichloro-4-morpholin-4-ylcarbonylpyridine; 4-(2,6-Dichloroisonicotinoyl)morpholine; 4-(2,6-Dichloro-4-pyridinecarbonyl)morpholine; 4-(2,6-Dichloropyridine-4-carbonyl)morpholine; 4-(2,6-Dichloro-4-pyridylcarbonyl)morpholine
EINECS	Contact for details

Quality Control

Every batch of 4-(2,6-Dichloroisonicotinoyl)Morpholine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.