Description

1H-Indazole, 5-Nitro-3-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block characterized by its nitro and trifluoromethyl substituents. This compound matters for its role as a critical synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other bioactive molecules targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the indazole core.
• Material Science: Serves as a building block for advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: Essential for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for client projects.

Basic Information

Product Name	1H-Indazole, 5-Nitro-3-(Trifluoromethyl)-
CAS No.	57631-07-9
Molecular Formula	C8H4F3N3O2
Molecular Weight	231.14 g/mol
Synonyms	5-Nitro-3-(trifluoromethyl)-1H-indazole; 3-(Trifluoromethyl)-5-nitro-1H-indazole; 5-Nitro-3-trifluoromethylindazole; 5-Nitro-3-trifluoromethyl-1H-indazole; 1H-Indazole-5-nitro-3-(trifluoromethyl)-; 57631-07-9; 5-Nitro-3-(trifluoromethyl)indazole
EINECS	Contact for details

Quality Control

Our 1H-Indazole, 5-Nitro-3-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere if prolonged exposure is anticipated.

Specification

Item	Specification
Appearance	Yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.