Description

Cibenzoline Succinate CAS NO 57625-97-5 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) primarily used in the synthesis of antiarrhythmic medications. Its significance lies in its critical role as the succinate salt form of cibenzoline, which offers enhanced stability and bioavailability for formulation. This compound is essential for pharmaceutical manufacturers and research institutions focused on developing and producing cardiovascular therapies, particularly class Ia antiarrhythmic agents.

Application

• Pharmaceutical API Synthesis: Primary use as the active pharmaceutical ingredient in the manufacture of antiarrhythmic drugs.
• Cardiovascular Research: Key reference standard and intermediate in preclinical and clinical research for heart rhythm disorders.
• Generic Drug Manufacturing: Essential for companies producing generic versions of cibenzoline-based medications.
• Formulation Development: Used in the development of various dosage forms, including tablets and capsules.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in laboratories.
• Biochemical Studies: Utilized in studies investigating sodium channel blockade and cardiac electrophysiology.

Basic Information

Product Name	Cibenzoline Succinate
CAS No.	57625-97-5
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	Cibenzoline Hydrogen Succinate; 2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole Succinate; Cibenol Succinate; Cifenline Succinate; Ro 22-7796; Pracizoline Succinate; UP 339-01
EINECS	Contact for details

Quality Control

Our Cibenzoline Succinate is manufactured under strict quality systems to ensure it meets the stringent requirements for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, to confirm compliance with in-house specifications and relevant pharmacopeial guidelines. A Certificate of Analysis (COA) documenting purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Unknown Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.