Description

6-Bromo-2H-chromene-3-carbonitrile is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring both a bromine substituent and a nitrile group, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for creating chromene and fused heterocyclic scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the synthesis of advanced crop protection agents and pesticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Acts as a monomer or precursor for the development of specialty polymers, organic semiconductors, and functional dyes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and cellular processes.
• Ligand and Catalyst Development: Useful for constructing complex chelating ligands or organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A fundamental building block for methodological studies in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	6-Bromo-2H-chromene-3-carbonitrile
CAS No.	57543-68-7
Molecular Formula	C10H6BrNO
Molecular Weight	236.07 g/mol
Synonyms	6-Bromo-2H-1-benzopyran-3-carbonitrile; 6-Bromo-3-cyano-2H-chromene; 6-Bromo-3-cyano-2H-1-benzopyran; 3-Cyano-6-bromo-2H-chromene; 6-Bromochromene-3-carbonitrile; 2H-1-Benzopyran-3-carbonitrile, 6-bromo-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to a cGMP-compliant quality management system to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.