Description

6-Chloro-2H-Chromene-3-Carbonitrile is a versatile and high-value chromene derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular scaffold, featuring a chloro-substituted chromene ring fused with a nitrile group, makes it an essential building block for constructing complex heterocyclic compounds. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for anti-inflammatory, antimicrobial, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex chromene, coumarin, and other fused heterocyclic systems.
• Material Science Precursor: Investigated for the synthesis of organic light-emitting diodes (OLEDs) and nonlinear optical (NLO) materials due to its chromophore properties.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized dyes and functional colorants.

Basic Information

Product Name	6-Chloro-2H-Chromene-3-Carbonitrile
CAS No.	57543-67-6
Molecular Formula	C10H6ClNO
Molecular Weight	191.61 g/mol
Synonyms	6-Chloro-2H-1-benzopyran-3-carbonitrile; 6-Chloro-3-cyano-2H-chromene; 6-Chloro-3-cyanochromene; 6-Chlorochromene-3-carbonitrile; 3-Cyano-6-chloro-2H-chromene; 57543-67-6; 6-Chloro-2H-1-benzopyran-3-carbonitrile
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Each batch of 6-Chloro-2H-Chromene-3-Carbonitrile is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our quality management system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.