Description

2-[n-[2,4,6-Triiodo-3-[(2-Methoxyacetyl)Amino]-5-(Methylaminocarbonyl)Benzoyl]-n-Methylamino]Acetic Acid is a high-purity, non-ionic iodinated organic compound, serving as a critical intermediate in the synthesis of advanced X-ray contrast media. Its precise molecular structure is engineered to provide excellent water solubility and low osmolality, which are essential for patient safety and diagnostic efficacy in medical imaging. This compound is primarily required by pharmaceutical manufacturers and advanced research institutions developing next-generation contrast agents for computed tomography (CT) and angiography.

Application

• Key Intermediate for Iodinated Contrast Media: Primary building block in the synthesis of modern, low-osmolar, non-ionic X-ray contrast agents.
• Pharmaceutical Research & Development (R&D): Used in the discovery and process development of new diagnostic imaging pharmaceuticals.
• Active Pharmaceutical Ingredient (API) Synthesis: A crucial precursor in the multi-step manufacturing process of final contrast agent APIs.
• Biomedical Research: Employed in studies investigating the pharmacokinetics, biodistribution, and safety profiles of iodinated compounds.
• Specialty Chemical Synthesis: Serves as a starting material for creating other complex, iodine-containing molecules for specialized applications.

Basic Information

Product Name	2-[n-[2,4,6-Triiodo-3-[(2-Methoxyacetyl)Amino]-5-(Methylaminocarbonyl)Benzoyl]-n-Methylamino]Acetic Acid
CAS No.	57469-58-6
Molecular Formula	C15H15I3N3O6
Molecular Weight	741.01 g/mol
Synonyms	Iomeprol Impurity; Iomeprol Intermediate; 5-Acetamido-2,4,6-triiodo-N-methyl-N-(2-methoxyacetyl)isophthalamic Acid; 2-[N-[2,4,6-Triiodo-3-[(2-methoxyacetyl)amino]-5-[(methylamino)carbonyl]benzoyl]-N-methylamino]acetic Acid; Acetic acid, 2-[N-[2,4,6-triiodo-3-[(2-methoxyacetyl)amino]-5-[(methylamino)carbonyl]benzoyl]-N-methylamino]-; Iopamidol Related Compound; Non-ionic Contrast Agent Intermediate
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict pharmaceutical-grade standards. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications. We support development and commercial projects requiring alignment with ICH Q7, GMP, and ISO 9001 quality management principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.