Description

H-Asn-Ome Hcl is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of L-asparagine. This compound serves as a crucial building block in peptide synthesis and pharmaceutical research, offering a protected side chain and activated carboxyl group for controlled coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel peptides, APIs, and bioactive molecules.

Application

• Peptide Synthesis: A key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and development of therapeutic peptides and active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed as a substrate or precursor in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Production: Serves as a chiral building block for the synthesis of complex organic molecules and specialty chemicals.
• Protecting Group Chemistry: Utilized in multi-step organic syntheses where selective protection of the asparagine side chain amide is required.

Basic Information

Product Name	H-Asn-Ome Hcl
CAS No.	57461-34-4
Molecular Formula	C5H11N3O3 • HCl
Molecular Weight	197.62 g/mol (Free base: 161.16)
Synonyms	L-Asparagine methyl ester hydrochloride; H-Asn-OMe•HCl; Methyl L-asparaginate hydrochloride; (S)-2-Amino-3-carbamoylpropanoic acid methyl ester hydrochloride; Asn-OMe HCl; Asparagine methyl ester HCl; Fmoc-Asn(Trt)-OH methyl ester precursor; Protected asparagine derivative
EINECS	Contact for details

Quality Control

Our H-Asn-Ome Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range available on COA
Chiral Purity	≥99.0% (by Chiral HPLC)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.