Description

5-Bromo-2-Chlorobenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which provides two distinct halogen handles for selective functionalization, enabling the construction of complex heterocyclic and pharmaceutical intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality raw materials for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromo and chloro substituents are leveraged for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Chemical Synthesis: A versatile scaffold for contract research organizations (CROs) and CDMOs producing custom fine chemicals for client projects.

Basic Information

Product Name	5-Bromo-2-Chlorobenzonitrile
CAS No.	57381-44-9
Molecular Formula	C7H3BrClN
Molecular Weight	216.46 g/mol
Synonyms	2-Chloro-5-bromobenzonitrile; 5-Bromo-2-chlorobenzene carbonitrile; 2-Chloro-5-bromobenzene nitrile; 5-Bromo-o-chlorobenzonitrile; Benzonitrile, 5-bromo-2-chloro-; (2-Chloro-5-bromophenyl) cyanide
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chlorobenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.