Description

2-Bromo-5-Chlorobenzonitrile is a versatile halogenated benzonitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of bromine and chlorine substituents on the aromatic ring, which enables selective functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its halogenated structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and liquid crystals, due to its electron-withdrawing nitrile group.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-5-Chlorobenzonitrile
CAS No.	57381-37-0
Molecular Formula	C7H3BrClN
Molecular Weight	216.46 g/mol
Synonyms	5-Chloro-2-bromobenzonitrile; 2-Bromo-5-chlorobenzene carbonitrile; 2-Bromo-5-chlorophenyl cyanide; Benzonitrile, 2-bromo-5-chloro-; 57381-37-0; 2-Br-5-Cl-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chlorobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against established specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.