Description

Oxyma CAS NO 57361-81-6 is a high-performance coupling reagent widely used in peptide synthesis to minimize racemization and enhance coupling efficiency. Its primary value lies in its ability to replace traditional, more hazardous reagents like HOBt and HOAt, offering a safer and more effective alternative for forming peptide bonds. This product is essential for research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the development and production of peptides, peptidomimetics, and other complex organic molecules.

Application

• As a superior coupling additive in solid-phase peptide synthesis (SPPS).
• For solution-phase peptide synthesis to achieve high-purity intermediates.
• In the synthesis of complex natural products and active pharmaceutical ingredients (APIs).
• As a key reagent for the preparation of peptide libraries for drug discovery.
• For the synthesis of peptidomimetics and other bioactive compounds.
• In conjugation chemistry for bioconjugation and labeling applications.

Basic Information

Product Name	Oxyma
CAS No.	57361-81-6
Molecular Formula	C4H5N3O3
Molecular Weight	143.10 g/mol
Synonyms	Ethyl 2-Cyano-2-(hydroxyimino)acetate; Ethyl Cyano(hydroxyimino)acetate; Oxyma Pure; Oxyma-B; Common Oxyma; (Ethoxycarbonyl)(hydroxyimino)acetonitrile; Oxyma Reagent; Coupling Reagent Oxyma
EINECS	Contact for details

Quality Control

Our Oxyma is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, purity by HPLC, and residual solvent content. We adhere to relevant industry standards and can provide material tailored to specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.