Description

Ac-D-Nva-Oh is a high-purity, custom-protected amino acid derivative, specifically N-Acetyl-D-Norvaline. This chiral building block is essential for advanced peptide synthesis and pharmaceutical research, offering precise stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic peptides and chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methods to incorporate D-configured norvaline residues into custom peptide sequences.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway investigations, and proteomics research.
• Chiral Catalyst & Ligand Development: Employed as a precursor for synthesizing chiral auxiliaries, catalysts, or ligands for asymmetric synthesis.
• Fine Chemical Production: Acts as a specialized building block for creating complex organic molecules with specific stereochemical requirements.

Basic Information

Product Name	Ac-D-Nva-Oh
CAS No.	57357-56-9
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	N-Acetyl-D-norvaline; (R)-2-Acetamidopentanoic acid; D-2-Acetamidopentanoic acid; Ac-D-Norvaline-OH; N-Acetyl-D-2-aminopentanoic acid; N-Ac-D-Nva-OH; N-Ac-D-Nva; Ac-D-Nva
EINECS	Contact for details

Quality Control

Our Ac-D-Nva-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.