Description

3-Methylisothiazole-5-Carbonitrile is a versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its reactive nitrile group and stable isothiazole core, enabling the construction of complex molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the isothiazole moiety.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized heterocyclic dyes and colorants.
• Coordination Chemistry: The nitrile group can act as a ligand for metal complexes used in catalysis or as functional materials.

Basic Information

Product Name	3-Methylisothiazole-5-Carbonitrile
CAS No.	57352-00-8
Molecular Formula	C5H4N2S
Molecular Weight	124.16 g/mol
Synonyms	5-Cyano-3-methylisothiazole; 3-Methyl-5-isothiazolecarbonitrile; 3-Methylisothiazole-5-carbonitrile; Isothiazole-5-carbonitrile, 3-methyl-; 3-Methyl-1,2-thiazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Methylisothiazole-5-Carbonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure consistency and purity for your critical synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by validated methods such as HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.