Description

(Tyr0)-C-Peptide (Human) CAS NO 57327-90-9 is a synthetic peptide analog of the human C-peptide, specifically lacking the tyrosine residue at position zero. This high-purity biochemical is a critical research tool for studying insulin biosynthesis, diabetes mellitus, and related metabolic disorders. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require precise and reliable peptide standards for assay development, quality control, and advanced biomedical research.

Application

• Biomedical Research Standard: Used as a primary reference standard in studies investigating proinsulin processing, insulin secretion, and β-cell function.
• Diagnostic Assay Development: Critical for the calibration and validation of immunoassays (e.g., ELISA, RIA) designed to measure C-peptide levels in clinical samples.
• Diabetes Research: A key reagent for exploring the pathophysiology of Type 1 and Type 2 diabetes, including studies on C-peptide's potential physiological effects.
• Pharmaceutical QC: Serves as a system suitability standard in the quality control of insulin and related therapeutic products.
• Metabolic Disorder Studies: Employed in research focused on insulin resistance, metabolic syndrome, and pancreatic islet cell biology.
• Antibody Production & Characterization: Used as an immunogen or binding target for generating and characterizing anti-C-peptide antibodies.

Basic Information

Product Name	(Tyr0)-C-Peptide (Human)
CAS No.	57327-90-9
Molecular Formula	C112H179N35O48S
Molecular Weight	2759.9 g/mol
Synonyms	Des-Tyr(0) C-Peptide (Human); Human C-Peptide (Tyr0); Proinsulin C-Peptide (Human, Tyr0); C-Peptide (1-31), human, Tyr(0)-; H-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-OH; Insulin C-Peptide Fragment; Connecting Peptide Analog
EINECS	Contact for details

Quality Control

Our (Tyr0)-C-Peptide (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (typically >95%), to ensure it meets the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 70.0% (by amino acid analysis)
Water Content (KF)	≤ 8.0%
Acetate Content (HPIC)	≤ 15.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.