Description

Boc-D-4-Fluorophe CAS NO 57292-45-2 is a high-purity, protected amino acid derivative, specifically the N-tert-butoxycarbonyl derivative of D-4-fluorophenylalanine. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic probes, and advanced biomaterials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Proteomics & Biochemical Research: Used to incorporate fluorinated aromatic side chains into peptides for structure-activity relationship (SAR) studies and metabolic stability investigations.
• Peptidomimetic Design: Essential for creating non-natural peptide analogs with enhanced bioavailability, receptor selectivity, and resistance to enzymatic degradation.
• Fluorine-Containing Compound Libraries: Serves as a foundational component in combinatorial chemistry for generating diverse screening libraries targeting various disease pathways.
• Diagnostic Agent Development: Employed in the synthesis of radiolabeled or fluorescently tagged peptides for imaging and diagnostic applications.

Basic Information

Product Name	Boc-D-4-Fluorophe CAS NO 57292-45-2
CAS No.	57292-45-2
Molecular Formula	C₁₄H₁₈FNO₄
Molecular Weight	283.30 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-4-fluorophenylalanine; Boc-D-4-Fluorophenylalanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoic acid; Boc-D-Phe(4-F)-OH; Boc-D-4-F-Phe-OH; tert-Butyloxycarbonyl-D-4-fluorophenylalanine; N-Boc-D-4-fluorophenylalanine; D-Boc-4-fluorophenylalanine
EINECS	Contact for details

Quality Control

Our Boc-D-4-Fluorophe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR). We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.5%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Specific Rotation [α]²⁰D	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.