Description

Human Inhibin A is a crucial glycoprotein hormone belonging to the transforming growth factor-beta (TGF-β) superfamily. It plays a vital role in regulating the endocrine system, specifically by suppressing follicle-stimulating hormone (FSH) secretion from the pituitary gland. This product is essential for researchers and developers in the biotechnology and pharmaceutical industries, particularly in the fields of reproductive health, endocrinology research, and diagnostic assay development.

Application

• Biomedical Research: Fundamental studies on the regulation of the hypothalamic-pituitary-gonadal axis, folliculogenesis, and spermatogenesis.
• Diagnostic Development: Critical raw material for the production of immunoassays and ELISA kits used to measure inhibin levels in clinical and research settings.
• Therapeutic Research: Investigation into potential therapeutic applications for fertility disorders, ovarian cancers, and other hormone-related conditions.
• Cell Culture & In Vitro Studies: Used as a bioactive component in cell culture media to study its effects on specific cell lines.
• Antibody Production: Serves as a key antigen for generating highly specific polyclonal and monoclonal antibodies.
• Quality Control & Standardization: Acts as a reference standard for calibrating assays and ensuring consistency in diagnostic manufacturing.

Basic Information

Product Name	Human Inhibin A
CAS No.	57285-09-3
Molecular Formula	C₁₉₈H₃₁₀N₅₆O₆₀S₁₈ (Approximate, for Inhibin A dimer)
Molecular Weight	~32 kDa (Glycosylated dimer)
Synonyms	INHA; Inhibin, alpha subunit; Folliculostatin; FRP; FSH-suppressing protein; Inhibin A; INHBA:INHA heterodimer; EINECS 260-595-7
EINECS	260-595-7

Quality Control

Our Human Inhibin A is produced and tested under stringent quality management systems. Each batch is characterized to ensure high biological activity and purity, with specifications tailored for research and diagnostic use. Comprehensive testing includes identity confirmation, purity assessment, and activity bioassays. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or with desiccant when possible.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (SDS-PAGE)	> 95%
Purity (RP-HPLC)	> 90%
Endotoxin	< 1.0 EU/μg
Biological Activity (Cell-based assay)	Contact for details
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.