Description

[6R-[6Alpha,7Beta(R*)]]-7-[(Formyloxy)Phenylacetamido]-3-[[(1-Methyl-1H-Tetrazol-5-Yl)Thio]Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a key advanced pharmaceutical intermediate, specifically a cephalosporin nucleus derivative. This compound is critical for the synthesis of third-generation cephalosporin antibiotics, offering a high-purity building block for complex pharmaceutical manufacturing. It is essential for research institutions and pharmaceutical companies engaged in the development and production of potent antibacterial agents.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial intermediate in the multi-step synthesis of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used as a reference standard and a starting material in medicinal chemistry for developing new antibacterial compounds.
• Antibiotic Manufacturing: A core component in the production of specific, high-efficacy cephalosporin drugs targeting resistant bacterial strains.
• Process Chemistry Optimization: Employed in scaling up and refining synthetic routes for cephalosporin-based pharmaceuticals in pilot plants and commercial production.
• Analytical Standard: Provides a high-purity standard for quality control (QC) and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical labs.

Basic Information

Product Name	[6R-[6Alpha,7Beta(R*)]]-7-[(Formyloxy)Phenylacetamido]-3-[[(1-Methyl-1H-Tetrazol-5-Yl)Thio]Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	57268-80-1
Molecular Formula	C₂₂H₂₁N₇O₆S₂
Molecular Weight	543.57 g/mol
Synonyms	7-[(Formyloxy)phenylacetamido]-3-[(1-methyl-1H-tetrazol-5-ylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefoperazone Intermediate; Cefoperazone Acid; Cefobid Intermediate; T-1551 Intermediate; 7-Formyloxy Cephalosporanic Acid Derivative; (6R,7R)-7-[(R)-2-(Formyloxy)-2-phenylacetamido]-3-[(1-methyl-1H-tetrazol-5-ylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our [6R-[6Alpha,7Beta(R*)]]-7-[(Formyloxy)Phenylacetamido]-3-[[(1-Methyl-1H-Tetrazol-5-Yl)Thio]Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.