Description

1-Boc-Piperazine is a high-purity, protected piperazine derivative widely used as a critical building block in organic synthesis. Its primary value lies in providing a reactive secondary amine group that is temporarily shielded by the acid-labile tert-butoxycarbonyl (Boc) protecting group, enabling precise, sequential reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs), complex molecules, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, including kinase inhibitors, antipsychotics, and antiviral agents.
• Peptide Synthesis: Used to introduce the piperazine moiety into peptide chains during solid-phase or solution-phase synthesis.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Chemical Research & Development: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and molecular libraries.
• Material Science: Can be utilized in the synthesis of specialty polymers, ligands for catalysis, and other functional materials.

Basic Information

Product Name	1-Boc-Piperazine
CAS No.	57260-72-7
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	1-Boc-piperazine; tert-Butyl 1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)piperazine; N-Boc-piperazine; Piperazine-1-carboxylic acid tert-butyl ester; 1-N-Boc-piperazine; Boc-Piperazine; 4-(tert-Butoxycarbonyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-Piperazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and loss on drying for moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.