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n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet CAS NO 57237-94-2
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CAS No.:57237-94-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet is a specialized synthetic peptide derivative, characterized by its dansyl (5-dimethylaminonaphthalene-1-sulfonyl) fluorophore group. This compound is of significant value in biochemical research and pharmaceutical development, primarily serving as a key intermediate or a fluorescent probe. It is essential for researchers and manufacturers in the fields of proteomics, enzyme studies, and advanced drug discovery who require high-purity, well-characterized building blocks. The product is supplied with full analytical documentation to ensure traceability and support critical R&D and production processes.
Application
- Fluorescent Labeling Agent: Used as a dansyl-based probe for labeling peptides, proteins, and other biomolecules to study structure, function, and interactions via fluorescence spectroscopy or microscopy.
- Protease Substrate/Analogue: Serves as a synthetic substrate or inhibitor in enzymatic assays to study the activity and specificity of proteases like elastase or other serine proteases.
- Pharmaceutical Intermediate: Acts as a critical building block in the synthesis of more complex peptide-based drug candidates or diagnostic agents.
- Biochemical Research: Employed in academic and industrial R&D for investigating peptide conformation, receptor-ligand binding, and cellular uptake mechanisms.
- Quality Control Standard: Utilized as a reference standard in analytical laboratories for method development and validation in HPLC or LC-MS systems.
Basic Information
| Item | Detail |
|---|---|
| Product Name | n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet |
| CAS No. | 57237-94-2 |
| Molecular Formula | C30H44N4O5 |
| Molecular Weight | 540.70 g/mol |
| Synonyms | Dansyl-Val-Ile-Ala-OEt; N-[[4-(Dimethylamino)-1-naphthalenyl]methylene]-L-valyl-L-isoleucyl-L-alanine ethyl ester; N-Dansyl-L-valyl-L-isoleucyl-L-alanine ethyl ester; Dns-Val-Ile-Ala-OEt; Ethyl N-dansyl-L-valyl-L-isoleucyl-L-alaninate; Fluorescent tripeptide derivative; 5-Dimethylaminonaphthalene-1-sulfonyl-Val-Ile-Ala ethyl ester |
| EINECS | Contact for details |
Quality Control
Our n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions, ideally with desiccant, to prevent degradation. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Yellow to light brown powder or solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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