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n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet CAS NO 57237-94-2


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CAS No.:57237-94-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet is a specialized synthetic peptide derivative, characterized by its dansyl (5-dimethylaminonaphthalene-1-sulfonyl) fluorophore group. This compound is of significant value in biochemical research and pharmaceutical development, primarily serving as a key intermediate or a fluorescent probe. It is essential for researchers and manufacturers in the fields of proteomics, enzyme studies, and advanced drug discovery who require high-purity, well-characterized building blocks. The product is supplied with full analytical documentation to ensure traceability and support critical R&D and production processes.

Application

  • Fluorescent Labeling Agent: Used as a dansyl-based probe for labeling peptides, proteins, and other biomolecules to study structure, function, and interactions via fluorescence spectroscopy or microscopy.
  • Protease Substrate/Analogue: Serves as a synthetic substrate or inhibitor in enzymatic assays to study the activity and specificity of proteases like elastase or other serine proteases.
  • Pharmaceutical Intermediate: Acts as a critical building block in the synthesis of more complex peptide-based drug candidates or diagnostic agents.
  • Biochemical Research: Employed in academic and industrial R&D for investigating peptide conformation, receptor-ligand binding, and cellular uptake mechanisms.
  • Quality Control Standard: Utilized as a reference standard in analytical laboratories for method development and validation in HPLC or LC-MS systems.

Basic Information

Item Detail
Product Name n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet
CAS No. 57237-94-2
Molecular Formula C30H44N4O5
Molecular Weight 540.70 g/mol
Synonyms Dansyl-Val-Ile-Ala-OEt; N-[[4-(Dimethylamino)-1-naphthalenyl]methylene]-L-valyl-L-isoleucyl-L-alanine ethyl ester; N-Dansyl-L-valyl-L-isoleucyl-L-alanine ethyl ester; Dns-Val-Ile-Ala-OEt; Ethyl N-dansyl-L-valyl-L-isoleucyl-L-alaninate; Fluorescent tripeptide derivative; 5-Dimethylaminonaphthalene-1-sulfonyl-Val-Ile-Ala ethyl ester
EINECS Contact for details

Quality Control

Our n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions, ideally with desiccant, to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance Yellow to light brown powder or solid
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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