Description

α-Amino-n-[(2S,5β)-3,3-Dimethyl-7-Oxo-2β-(1H-Tetrazol-5-Yl)-4-Thia-1-Azabicyclo[3.2.0]Heptan-6α-Yl]-4-Hydroxybenzeneacetamide is a high-purity pharmaceutical intermediate, specifically a key β-lactam derivative. This compound is critical for ensuring the structural integrity and bioactivity of advanced cephalosporin antibiotics. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the synthesis of next-generation antibacterial agents.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A crucial building block in the production of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of novel β-lactam compounds with improved efficacy.
• Process Chemistry: Serves as a key intermediate in scale-up and optimization of antibiotic manufacturing processes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and regulatory testing of finished pharmaceutical products.

Basic Information

Product Name	α-Amino-n-[(2S,5β)-3,3-Dimethyl-7-Oxo-2β-(1H-Tetrazol-5-Yl)-4-Thia-1-Azabicyclo[3.2.0]Heptan-6α-Yl]-4-Hydroxybenzeneacetamide
CAS No.	57089-17-5
Molecular Formula	C₁₉H₂₁N₇O₄S
Molecular Weight	443.48 g/mol
Synonyms	7β-[(Z)-2-(2-Amino-4-thiazolyl)-2-hydroxyiminoacetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylic acid (syn isomer); Cefmenoxime Impurity; Cefmenoxime Intermediate; (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (related derivative); SC E 1365 Intermediate; β-Lactam antibiotic intermediate; 4-Thia-1-azabicyclo[3.2.0]heptane derivative
EINECS	Contact for details

Quality Control

Our α-Amino-n-[(2S,5β)-3,3-Dimethyl-7-Oxo-2β-(1H-Tetrazol-5-Yl)-4-Thia-1-Azabicyclo[3.2.0]Heptan-6α-Yl]-4-Hydroxybenzeneacetamide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific pharmaceutical grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.