Description

L-Alanine, n-(1,1-Dimethylethoxy)- (9Ci) is a protected derivative of the essential amino acid L-alanine, where the amino group is shielded by a tert-butoxycarbonyl (Boc) group. This chemical modification is critical for enabling selective peptide synthesis and protecting sensitive functional groups during complex organic reactions. It serves as a vital building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel peptides, active pharmaceutical ingredients (APIs), and other fine chemicals.

Application

• Peptide Synthesis: A key protected amino acid intermediate in solid-phase and solution-phase peptide synthesis for research and pharmaceutical manufacturing.
• Pharmaceutical Intermediates: Used in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) requiring selective amino group protection.
• Bioconjugation & Linker Chemistry: Employed in the preparation of peptide-based linkers for antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Biochemical Research: Serves as a reagent in proteomics research, enzyme studies, and the investigation of metabolic pathways.
• Fine Chemical Production: Acts as a chiral building block for the synthesis of non-peptidic compounds in agrochemical and specialty chemical applications.

Basic Information

Product Name	L-Alanine, n-(1,1-Dimethylethoxy)- (9Ci)
CAS No.	57022-44-3
Molecular Formula	C8H17NO4
Molecular Weight	191.23 g/mol
Synonyms	Boc-L-alanine; N-(tert-Butoxycarbonyl)-L-alanine; (S)-2-((tert-Butoxycarbonyl)amino)propanoic acid; N-Boc-L-alanine; Boc-Ala-OH; L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-; N-tert-Butoxycarbonyl-L-alanine; 2-[(tert-Butoxycarbonyl)amino]propanoic acid
EINECS	Contact for details

Quality Control

Our Boc-L-alanine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric purity, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range provided on COA
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.