Description

1-(Diphenylphosphino)-1H-Azepine 1-Oxide is a specialized organophosphorus compound featuring a unique seven-membered azepine ring. This heterocyclic phosphine oxide is valued for its role as a versatile ligand and building block in advanced synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical and fine chemical industries for the development of novel catalysts and complex organic molecules.

Application

• Catalyst Ligand in Cross-Coupling Reactions: Serves as a key ligand for palladium, nickel, or other transition metal catalysts in C-C and C-X bond-forming reactions like Suzuki, Heck, and Negishi couplings.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing complex nitrogen-containing heterocycles.
• Material Science Research: Acts as a precursor or functional additive in the development of advanced polymeric materials and coordination complexes.
• Asymmetric Synthesis: Potential application as a chiral auxiliary or ligand in enantioselective catalytic processes for producing optically pure compounds.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as a component in the synthesis of electron-transport or host materials for OLED devices.
• Agrochemical Research: Employed in the synthesis of novel ligands for catalytic systems used in creating new crop protection agents.

Basic Information

Product Name	1-(Diphenylphosphino)-1H-Azepine 1-Oxide
CAS No.	56909-19-4
Molecular Formula	C18H18NOP
Molecular Weight	295.32 g/mol
Synonyms	1-(Diphenylphosphino)-1H-azepine 1-oxide; 1H-Azepine, 1-(diphenylphosphinyl)-; 1-(Diphenylphosphinyl)-1H-azepine; 1-(Diphenylphosphoryl)-1H-azepine; Azepine, 1-(diphenylphosphinyl)-; 1-(Diphenylphosphino)azepine 1-oxide; 1-(Diphenylphosphino)azepine oxide
EINECS	Contact for details

Quality Control

Our 1-(Diphenylphosphino)-1H-Azepine 1-Oxide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.