Description

Sodium (6R-Trans)-7-Amino-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate is a key sodium salt derivative of a cephalosporin nucleus, essential for the synthesis of advanced β-lactam antibiotics. This high-purity intermediate is critical for ensuring the efficacy, stability, and regulatory compliance of the final active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of cephalosporin-class antibiotics.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of various semi-synthetic cephalosporin antibiotics.
• API Manufacturing: Used in the production of active pharmaceutical ingredients (APIs) for broad-spectrum antibacterial drugs.
• Research & Development: Serves as a key starting material in medicinal chemistry for developing new β-lactam derivatives with improved properties.
• Process Chemistry: Employed in scale-up and optimization of antibiotic synthesis routes in pilot plants and commercial production.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Sodium (6R-Trans)-7-Amino-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
CAS No.	56871-82-0
Molecular Formula	C9H10N3NaO3S
Molecular Weight	263.25 g/mol
Synonyms	7-ACA Sodium Salt; 7-Aminocephalosporanic Acid Sodium Salt; Sodium 7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 7-ACA Na; Sodium 7-ACA; (6R,7R)-7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt; Cephalosporin 7-ACA Sodium; 7-ADCA related compound sodium salt
EINECS	Contact for details

Quality Control

Our Sodium 7-ACA is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with cGMP guidelines and relevant pharmacopoeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
pH (10% solution)	6.0 - 8.0
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.