Description

Methyl 2-(2-Amino-4-Fluorophenyl)Acetate is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its bifunctional nature, featuring both a reactive amino group and a protected carboxylic acid moiety, enabling its use in constructing complex molecular architectures. It is primarily sought after by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used to develop novel herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Dye and Sensor Chemistry: Incorporated into the backbone of organic fluorophores and molecular sensors due to its aromatic amine structure.
• Peptidomimetic Research: Utilized in the design and synthesis of peptide analogs and constrained scaffolds for medicinal chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated aromatic segments.

Basic Information

Product Name	Methyl 2-(2-Amino-4-Fluorophenyl)Acetate
CAS No.	56827-32-8
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	2-Amino-4-fluorobenzeneacetic acid methyl ester; Methyl (2-amino-4-fluorophenyl)acetate; 4-Fluoro-2-aminophenylacetic acid methyl ester; Methyl α-(2-amino-4-fluorophenyl)acetate; 2-(2-Amino-4-fluorophenyl)acetic acid methyl ester; (2-Amino-4-fluorophenyl)acetic acid methyl ester; Methyl 2-amino-4-fluorobenzeneacetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(2-Amino-4-Fluorophenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider under an inert atmosphere (nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.