Description

Tuftsin, Leu(1)- CAS NO 56694-23-6 is a synthetic, biologically active tetrapeptide analog of the natural immunomodulatory peptide tuftsin. This compound is of significant interest for its enhanced stability and potent immunostimulatory properties compared to its native counterpart. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for advanced immunological studies and as a key intermediate in the development of novel therapeutic agents.

Application

• Immunological Research: A critical tool for studying macrophage activation, phagocytosis, and the modulation of innate immune responses in vitro and in vivo.
• Drug Discovery & Development: Serves as a lead compound or a structural scaffold for designing new immunotherapies, anti-infective agents, and cancer vaccines.
• Biopharmaceutical Intermediates: Used as a high-purity building block in the synthesis of more complex peptide-based pharmaceuticals and conjugates.
• Cell Culture & Assay Development: Employed to stimulate immune cells in culture systems to model disease states or evaluate drug efficacy.
• Preclinical Studies: Investigated for its potential therapeutic effects in animal models of infection, immunodeficiency, and certain cancers.

Basic Information

Product Name	Tuftsin, Leu(1)- CAS NO 56694-23-6
CAS No.	56694-23-6
Molecular Formula	C₂₃H₄₀N₈O₇
Molecular Weight	540.61 g/mol
Synonyms	L-Leucyl-L-threonyl-L-lysyl-L-proline; [Leu1]-Tuftsin; Leu-Thr-Lys-Pro; NSC 351358; Thr-Lys-Pro-Leu; Tuftsin (Leu1-); H-Leu-Thr-Lys-Pro-OH; Immunostimulant peptide [Leu1]tuftsin
EINECS	Contact for details

Quality Control

Our Tuftsin, Leu(1)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Within ± 10% of theoretical
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.