Description

(2,2-Dimethyl-1-Oxopropyl)Methyl(Trifluoromethyl)Phosphine is a specialized organophosphorus compound featuring a unique trifluoromethylphosphine moiety, making it a valuable reagent in advanced chemical synthesis. Its primary commercial value lies in its role as a key ligand precursor and building block for creating novel catalysts and functional materials. This high-purity intermediate is essential for research and development in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular control is required.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorine-containing drug candidates.
• Catalyst Ligand Synthesis: Used as a precursor for synthesizing specialized phosphine ligands, which are integral to transition metal catalysis in fine chemical production.
• Agrochemical Research: Employed in the development of new-generation pesticides and herbicides, leveraging the biological activity imparted by the phosphorus and fluorine atoms.
• Material Science: Acts as a monomer or additive in the creation of advanced polymers and coatings with specific thermal or chemical resistance properties.
• Organic Synthesis Reagent: Facilitates key phosphorylation and carbon-phosphorus bond formation reactions in complex molecule construction.
• Chemical Research & Development: A vital tool for academic and industrial R&D labs exploring new reaction methodologies and organophosphorus chemistry.

Basic Information

Item	Detail
Product Name	(2,2-Dimethyl-1-Oxopropyl)Methyl(Trifluoromethyl)Phosphine
CAS No.	56630-68-3
Molecular Formula	C7H12F3OP
Molecular Weight	200.14 g/mol
Synonyms	Methyl(trifluoromethyl)(3,3-dimethyl-2-oxobutyl)phosphine; Pivaloylphosphine derivative; (3,3-Dimethyl-2-oxobutyl)methyl(trifluoromethyl)phosphine; Trifluoromethyl(pivaloylmethyl)methylphosphine; (2,2-Dimethylpropionyl)methyl(trifluoromethyl)phosphine; Pivaloylmethyl(trifluoromethyl)methylphosphine; 56630-68-3; Methyl(trifluoromethyl)(pivaloylmethyl)phosphine
EINECS	Contact for details

Quality Control

Every batch of (2,2-Dimethyl-1-Oxopropyl)Methyl(Trifluoromethyl)Phosphine is manufactured and tested under strict quality management protocols to ensure high purity and consistency. Our quality control process includes rigorous analytical testing, with specifications tailored to meet the demanding requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), this material must be stored under a dry, inert gas (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed when not in use to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC or HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.