Description

n-[(tert-Butoxy)Carbonyl]-n-Methylglycyl-n-Methylglycine is a high-purity, protected dipeptide derivative widely used as a critical building block in organic synthesis. This compound is valued for its role in constructing complex peptide chains, where the tert-butoxycarbonyl (Boc) group provides essential protection for the amine functionality during multi-step reactions. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Research & Development: Used in academic and industrial R&D for studying peptide structure-activity relationships (SAR) and developing new drug candidates.
• Bioconjugation: Serves as a linker or spacer molecule in the conjugation of peptides to other biomolecules, polymers, or surfaces for diagnostic and therapeutic applications.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• API Synthesis: Integral in the multi-step synthetic pathways for Active Pharmaceutical Ingredients (APIs) that contain modified glycine or methylglycine motifs.
• Biochemical Tool: Used in the preparation of enzyme substrates, inhibitors, or probes for biochemical and pharmacological studies.

Basic Information

Product Name	n-[(tert-Butoxy)Carbonyl]-n-Methylglycyl-n-Methylglycine
CAS No.	56612-14-7
Molecular Formula	C11H20N2O5
Molecular Weight	260.29 g/mol
Synonyms	Boc-N-Me-Gly-N-Me-Gly-OH; Boc-N-methylglycyl-N-methylglycine; (tert-Butoxycarbonyl)methylaminoacetic acid 2-[(methylamino)acetyl] ester; N-(tert-Butoxycarbonyl)-N-methylglycyl-N-methylglycine; N-Boc-N-methylglycyl-N-methylglycine; Nα-(tert-Butoxycarbonyl)-Nα-methylglycyl-N-methylglycine; 2-[[(2-[(tert-butoxycarbonyl)(methyl)amino]acetyl)(methyl)amino]acetic acid]; Boc-MeGly-MeGly
EINECS	Contact for details

Quality Control

Our n-[(tert-Butoxy)Carbonyl]-n-Methylglycyl-n-Methylglycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for GLP or GMP workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.