Description

3,3,3-Trifluoro-2-Phenyl-Propanoic Acid is a high-value fluorinated aromatic building block characterized by its trifluoromethyl and carboxylic acid functional groups. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced synthesis. It is primarily sought after by pharmaceutical R&D and agrochemical manufacturers for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of anti-inflammatory and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Advanced Material Science: Employed in the synthesis of specialty polymers and coatings that require chemical and thermal resistance.
• Organic Synthesis Reagent: A versatile reagent for introducing the 3,3,3-trifluoro-2-phenylpropionyl moiety into complex molecules via coupling reactions.

Basic Information

Product Name	3,3,3-Trifluoro-2-Phenyl-Propanoic Acid
CAS No.	56539-85-6
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	2-Phenyl-3,3,3-trifluoropropanoic Acid; α-Phenyl-β,β,β-trifluoropropionic Acid; 3,3,3-Trifluoro-2-phenylpropionic Acid; (RS)-3,3,3-Trifluoro-2-phenylpropanoic Acid; (±)-3,3,3-Trifluoro-2-phenylpropanoic Acid; TFPPA; Benzenepropanoic acid, 3,3,3-trifluoro-
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoro-2-Phenyl-Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.