Description

2-([(Benzyloxy)Carbonyl]Amino)-2-Hydroxyacetic Acid is a protected amino acid derivative, specifically a Cbz-protected glycolic acid amide, which serves as a crucial synthetic intermediate. This compound is valued for its role in facilitating the controlled synthesis and modification of peptides and other bioactive molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis for the controlled introduction of the glycolic acid moiety.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Employed as a tool compound for studying enzyme inhibition and proteolytic pathways.
• Organic Synthesis: Acts as a versatile precursor for the preparation of more complex heterocyclic compounds and functionalized amino acids.

Basic Information

Product Name	2-([(Benzyloxy)Carbonyl]Amino)-2-Hydroxyacetic Acid
CAS No.	56538-57-9
Molecular Formula	C10H11NO5
Molecular Weight	225.20 g/mol
Synonyms	N-Carbobenzoxyglycolamide; N-Cbz-glycolamide; (Benzyloxycarbonylamino)-hydroxyacetic Acid; 2-[[(Phenylmethoxy)carbonyl]amino]-2-hydroxyacetic acid; Z-Glycolamide; N-(Benzyloxycarbonyl)glycolamide; 2-Hydroxy-2-[(phenylmethoxy)formamido]acetic acid; Glycolic acid, 2-[(benzyloxycarbonyl)amino]-
EINECS	Contact for details

Quality Control

Our 2-([(Benzyloxy)Carbonyl]Amino)-2-Hydroxyacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.