Description

Lipoteichoic Acid is a crucial amphiphilic glycopolymer found in the cell walls of Gram-positive bacteria. It plays a significant role in immunological research and pharmaceutical development due to its potent immunostimulatory properties. This high-purity biochemical is essential for researchers and manufacturers in the fields of vaccine development, immunology, and microbiology, where it is used to study host-pathogen interactions and inflammatory responses.

Application

• Immunological Research: As a key pathogen-associated molecular pattern (PAMP) to study Toll-like receptor 2 (TLR2) signaling and innate immune activation.
• Vaccine Adjuvant Development: Investigated for its potential to enhance immune responses in next-generation vaccine formulations.
• Inflammation Studies: Used in vitro and in vivo to model and investigate the mechanisms of septic shock and systemic inflammation.
• Pharmaceutical Screening: Serves as a target or tool compound in high-throughput screens for novel anti-inflammatory or anti-infective agents.
• Diagnostic Reagent Production: Employed in the development of immunoassays and diagnostic kits for bacterial detection.
• Cell Biology & Microbiology: Used to study bacterial cell wall structure, function, and interactions with host cells.

Basic Information

Product Name	Lipoteichoic Acid
CAS No.	56411-57-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LTA; Teichoic Acid, Lipo-; Lipoteichoate; Staphylococcus aureus Lipoteichoic Acid; Gram-Positive Bacterial Cell Wall Polymer; TLR2 Ligand; Glycerol Teichoic Acid
EINECS	Contact for details

Quality Control

Our Lipoteichoic Acid is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment and functional activity validation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as identity, purity, endotoxin levels, and biological potency to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Cell-based assay)	Stimulates TLR2-dependent NF-κB activation
Water Content (KF)	< 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.