Description

1,3,5(10)-Estratrien-17-α-Ethynyl-3,6-Alpha, 17-β-Triol is a high-purity, synthetic steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is essential for research institutions and pharmaceutical manufacturers focused on developing next-generation hormone therapies and targeted treatments.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of steroidal drugs and novel therapeutic compounds.
• Research & Development: Used in biochemical research to study hormone receptor interactions and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Studies: Employed in the development and testing of new drug candidates targeting estrogen-related pathways.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic and medicinal chemistry.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of synthetic routes for complex molecules.

Basic Information

Product Name	1,3,5(10)-Estratrien-17-α-Ethynyl-3,6-Alpha, 17-β-Triol
CAS No.	56324-28-8
Molecular Formula	C20H24O3
Molecular Weight	312.41 g/mol
Synonyms	17α-Ethynylestra-1,3,5(10)-triene-3,6α,17β-triol; 17α-Ethynyl-3,6α,17β-estratriol; 17α-Ethynylestra-1,3,5(10)-triene-3,6α,17β-triol; 6α,17β-Dihydroxy-17α-ethynylestra-1,3,5(10)-trien-3-ol; 17α-Ethynyl-6α,17β-dihydroxyestra-1,3,5(10)-trien-3-ol; Ethynyl Estradiol Dihydroxylated Derivative
EINECS	Contact for details

Quality Control

Our 1,3,5(10)-Estratrien-17-α-Ethynyl-3,6-Alpha, 17-β-Triol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.