Description

Methocarbamol β-D-Glucuronide CAS NO 56305-74-9 is a major metabolite of the centrally acting muscle relaxant methocarbamol. This compound is of significant value in pharmaceutical research and development, particularly for pharmacokinetic and metabolic studies. It serves as a critical reference standard for analytical laboratories in the pharmaceutical and biotechnology sectors, enabling accurate quantification and characterization of methocarbamol and its metabolites in biological matrices.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for analytical method development and validation.
• Bioanalytical Research: Essential for quantifying methocarbamol and its metabolites in plasma, serum, and urine during preclinical and clinical trials.
• Metabolic Pathway Studies: Used to investigate the glucuronidation pathway and metabolic fate of methocarbamol in vivo.
• Quality Control (QC) Testing: Employed in pharmaceutical QC laboratories to ensure the accuracy and reliability of assay methods for drug products containing methocarbamol.
• Forensic Toxicology: Aids in the identification and confirmation of methocarbamol use in forensic and clinical toxicology screenings.
• Doping Control: Potential application in sports anti-doping programs to detect the misuse of muscle relaxants.

Basic Information

Product Name	Methocarbamol β-D-Glucuronide
CAS No.	56305-74-9
Molecular Formula	C17H25NO11
Molecular Weight	419.38 g/mol
Synonyms	Methocarbamol glucuronide; 3-(2-Methoxyphenoxy)-1,2-propanediol 1-(β-D-glucopyranosiduronic acid); Robaxin glucuronide; Guaifenesin carbamate glucuronide; Methocarbamol β-D-glucopyranosiduronic acid; 1,2-Propanediol, 3-(2-methoxyphenoxy)-, 1-(β-D-glucopyranosiduronate); Metocarbamol glucuronide
EINECS	Contact for details

Quality Control

Our Methocarbamol β-D-Glucuronide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing batch-specific results for purity, impurities, and residual solvents. Our quality commitment ensures material suitability for use as a high-purity reference standard in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.