Description

Cefuroxime Sodium is a second-generation cephalosporin antibiotic in its sodium salt form, offering enhanced stability and solubility for pharmaceutical manufacturing. Its primary value lies in its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria, making it a critical intermediate for sterile injectable formulations. This product is essential for pharmaceutical companies and research institutions developing parenteral antibiotics for the treatment of serious infections, including respiratory tract, urinary tract, and skin structure infections.

Application

• Active Pharmaceutical Ingredient (API): Primary use as the key active component in the manufacture of sterile injectable antibiotic formulations.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the synthesis of more complex cephalosporin-based drug products.
• Research & Development: Used in microbiological and pharmacological research to study antibiotic efficacy, resistance patterns, and new combination therapies.
• Hospital Formulations: Employed in the preparation of ready-to-use injections or infusion bags within hospital pharmacy settings.
• Veterinary Medicine: Applied in the development of antibacterial treatments for veterinary use.

Basic Information

Product Name	Cefuroxime Sodium
CAS No.	56238-63-2
Molecular Formula	C16H15N4NaO8S
Molecular Weight	446.37 g/mol
Synonyms	(6R,7R)-3-[(Carbamoyloxy)methyl]-7-[[(2Z)-2-(2-furyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; Sodium (6R,7R)-3-[(aminocarbonyl)oxy]methyl]-7-[(Z)-2-(2-furyl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefuroxime Sodium Salt; Zinacef (brand name sodium salt form); Cefuroximum Natricum; Cefuroxime Na; (Z)-Cefuroxime Sodium
EINECS	260-073-3

Quality Control

Our Cefuroxime Sodium is manufactured under strict quality systems and undergoes rigorous analytical testing to ensure it meets the highest standards for pharmaceutical use. Quality is assured through compliance with current Good Manufacturing Practices (cGMP) and relevant pharmacopeial monographs. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	6.0 - 8.5
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.