Description

n-Heptafluorobutyrylproline is a specialized fluorinated derivative of the amino acid proline, designed for high-performance analytical and synthetic applications. This compound is valued for its role as a key derivatization agent, enhancing the detection and analysis of complex molecules in sensitive instrumentation. It is primarily utilized by research institutions and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors for method development and trace analysis.

Application

• Chiral Derivatization Agent: Used for the resolution and analysis of enantiomeric compounds via chromatography.
• Mass Spectrometry (MS) Enhancement: Serves as a derivatizing reagent to improve ionization efficiency and detection sensitivity of analytes in LC-MS and GC-MS workflows.
• Pharmaceutical Impurity Profiling: Employed in the identification and quantification of trace impurities and degradation products in active pharmaceutical ingredients (APIs).
• Metabolomics and Proteomics Research: Facilitates the analysis of amino acids, peptides, and small molecule metabolites in complex biological samples.
• Chemical Synthesis Intermediate: Acts as a building block for the synthesis of more complex fluorinated molecules with potential biological activity.
• Forensic and Doping Analysis: Applied in advanced analytical methods for the precise detection of specific compounds in forensic toxicology and anti-doping controls.

Basic Information

Product Name	n-Heptafluorobutyrylproline
CAS No.	56236-41-0
Molecular Formula	C9H8F7NO3
Molecular Weight	311.16 g/mol
Synonyms	L-Proline, 1-[(heptafluorobutanoyl)oxy]-; 1-Heptafluorobutyrylproline; N-Heptafluorobutyryl-L-proline; HFB-Pro-OH; Heptafluorobutyric acid proline derivative; Proline heptafluorobutyrate; N-(Perfluorobutyryl)proline; L-Proline, N-(heptafluorobutanoyl)-
EINECS	Contact for details

Quality Control

Our n-Heptafluorobutyrylproline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including chromatographic purity assessment and structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); ensure the container is kept sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.