Description

4'-Deoxydoxorubicinol 7-Deoxyaglycone is a key chemical intermediate and reference standard derived from the anthracycline class of compounds. This compound is of significant importance in pharmaceutical research and development, particularly for the synthesis and analytical study of doxorubicin derivatives and related anticancer agents. It is primarily needed by research institutions, pharmaceutical development laboratories, and manufacturers of high-purity active pharmaceutical ingredients (APIs) and analytical standards.

Application

• Pharmaceutical Intermediate: A critical building block in the synthetic pathways for novel anthracycline-based chemotherapeutic agents.
• Reference Standard: Used as a high-purity standard in analytical chemistry for method development, validation, and quality control (QC) of doxorubicin and its metabolites.
• Biochemical Research: Employed in studies investigating the metabolism, mechanism of action, and structure-activity relationships (SAR) of anthracycline drugs.
• Impurity Profiling: Serves as a characterized impurity standard to monitor and control the quality of doxorubicin API during manufacturing.
• Metabolite Studies: Utilized in pharmacokinetic and pharmacodynamic research to understand the biological fate of anthracycline compounds.

Basic Information

Product Name	4'-Deoxydoxorubicinol 7-Deoxyaglycone
CAS No.	56149-23-6
Molecular Formula	C26H29NO10
Molecular Weight	515.51 g/mol
Synonyms	7-Deoxy-4'-deoxydoxorubicinol Aglycone; 4'-Deoxydoxorubicinol Aglycone; 7-Deoxyaglycone of 4'-Deoxydoxorubicinol; Doxorubicin Impurity; Doxorubicin Related Compound; 4'-Deoxy-7-deoxydoxorubicinol; (7S,9S)-7-((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
EINECS	Contact for details

Quality Control

Our 4'-Deoxydoxorubicinol 7-Deoxyaglycone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Reddish-orange to brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on dried basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.