Description

3'-Hydroxycephamycin B is a semi-synthetic β-lactam antibiotic derivative belonging to the cephamycin class. This compound is a key intermediate in the research and development of advanced antibacterial agents, offering a crucial structural scaffold for further chemical modification. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology firms, and academic institutions engaged in the synthesis of novel antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel cephamycin and cephalosporin antibiotics.
• Antibacterial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) and mechanisms of action against Gram-positive and Gram-negative bacteria.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.
• Process Chemistry Development: Integral to scaling up and optimizing synthetic routes for next-generation β-lactam antibiotics in pilot plants.
• Academic & Institutional Research: Supports fundamental research in medicinal chemistry, pharmacology, and microbiology within universities and government research institutes.

Basic Information

Product Name	3'-Hydroxycephamycin B
CAS No.	56083-50-2
Molecular Formula	C16H21N3O9S
Molecular Weight	431.42 g/mol
Synonyms	(6R,7R)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7α-Methoxy Derivative; 3'-Hydroxycephamycin B; 7α-Methoxy-3'-hydroxycephalosporin derivative; Antibiotic intermediate 56083-50-2
EINECS	Contact for details

Quality Control

Our 3'-Hydroxycephamycin B is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent controls for related substances and residual solvents. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.