Description

2(3H)-Naphthalenone, 3-Fluoro-4,4A,5,6,7,8-Hexahydro- is a specialized fluorinated hexahydronaphthalenone derivative, a high-value intermediate prized for its unique structural motif. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, particularly in advanced pharmaceutical research and fine chemical manufacturing. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorinated, partially hydrogenated naphthalene scaffolds into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, or pesticides where the fluorinated, saturated ring system can enhance biological activity and environmental stability.
• Material Science Research: Acts as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials that require specific fluorinated aromatic/aliphatic hybrid structures.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex natural product analogs or for methodology development in catalytic hydrogenation and fluorination chemistry.
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing novel aroma chemicals with modified stability and scent profiles due to the fluorine atom and hydrogenated backbone.

Basic Information

Product Name	2(3H)-Naphthalenone, 3-Fluoro-4,4A,5,6,7,8-Hexahydro-
CAS No.	56003-61-3
Molecular Formula	C₁₀H₁₁FO
Molecular Weight	166.19 g/mol
Synonyms	3-Fluoro-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone; 3-Fluoro-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one; 3-Fluoro-1,2,3,4,4a,5,6,7-octahydronaphthalen-2-one; 3-Fluorooctahydro-2-naphthalenone; Fluorinated hexahydronaphthalenone; 56003-61-3; 3-Fluoro-4,4a,5,6,7,8-hexahydro-2H-naphthalen-2-one
EINECS	Contact for details

Quality Control

Our 2(3H)-Naphthalenone, 3-Fluoro-4,4A,5,6,7,8-Hexahydro- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential contamination. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.