Description

Proglucagon is a prohormone and the precursor molecule to several important peptide hormones, including glucagon, GLP-1, and GLP-2. This compound is of significant value in biochemical and pharmaceutical research for studying metabolic pathways, hormone processing, and the development of related therapeutics. It is primarily utilized by research institutions, diagnostic manufacturers, and biotechnology companies focused on endocrinology, diabetes, and gastrointestinal disorders.

Application

• Biochemical Research: Used as a critical reference standard and substrate in studies of prohormone convertase activity and peptide hormone biosynthesis.
• Pharmaceutical Development: Serves as a starting material or intermediate in the research and development of glucagon-like peptide (GLP) based therapies.
• Diagnostic Reagent Manufacturing: Employed in the production of immunoassays and test kits for measuring glucagon, GLP-1, or related peptides.
• Cell Biology Studies: Applied in in vitro and cellular models to investigate the regulation and secretion of enteroendocrine hormones.
• Metabolic Disorder Research: A key tool for understanding the pathophysiology of diabetes, obesity, and other metabolic conditions.

Basic Information

Product Name	Proglucagon
CAS No.	55963-74-1
Molecular Formula	CnHmNoOpSq (Contact for details)
Molecular Weight	Contact for details
Synonyms	Glucagon Precursor; Glucagon-Like Peptide 1/2 Precursor; Pro-Glucagon; GLP-1/2 Prohormone; Enteroglucagon; Oxyntomodulin Precursor; GRPP; Major Proglucagon Fragment
EINECS	Contact for details

Quality Control

Our Proglucagon is produced and handled under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Biological Activity	Assessed by functional assay (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.