Description

5-Chloro-2-Methoxybenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and methoxy substituents, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by the pharmaceutical and agrochemical industries for the research and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders and inflammatory conditions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its benzonitrile core provides structural diversity.
• Liquid Crystal Materials: Acts as a precursor in the manufacturing of liquid crystal compounds for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or host materials in OLED device fabrication.
• Dye and Pigment Manufacturing: Utilized in the synthesis of specialized dyes and organic pigments due to its reactive nitrile group.
• Research & Development: Employed in academic and industrial R&D labs for method development and exploring novel chemical reactions.
• Polymer Chemistry: Can be incorporated as a monomer or modifier to create polymers with specific thermal or optical properties.

Basic Information

Product Name	5-Chloro-2-Methoxybenzonitrile
CAS No.	55877-79-7
Molecular Formula	C8H6ClNO
Molecular Weight	167.59 g/mol
Synonyms	2-Methoxy-5-chlorobenzonitrile; 5-Chloro-2-methoxybenzenecarbonitrile; 2-Cyano-4-chloroanisole; 4-Chloro-2-cyanomethoxybenzene; 5-Chloro-o-anisonitrile; Benzonitrile, 5-chloro-2-methoxy-; 5-Chloro-2-methoxy phenyl cyanide
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	85 - 89 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.