Description

1-Hydroxycyclobutane-1-Carbonitrile is a versatile, high-purity organic building block featuring a cyclobutane ring substituted with both hydroxyl and nitrile functional groups. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is particularly sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by fine chemical manufacturers for producing specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in the synthesis of constrained analogs and bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its rigid carbon skeleton for enhanced biological activity.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, including ligands, catalysts, and advanced polymers.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including ring-opening and functional group transformation reactions.
• Material Science: Potential building block for high-performance polymers and resins with tailored thermal and mechanical properties.

Basic Information

Product Name	1-Hydroxycyclobutane-1-Carbonitrile
CAS No.	55767-58-3
Molecular Formula	C5H7NO
Molecular Weight	97.12 g/mol
Synonyms	1-Hydroxycyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-hydroxy-; 1-Cyano-1-hydroxycyclobutane; 1-Hydroxy-1-cyclobutanecarbonitrile; α-Hydroxycyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-Hydroxycyclobutane-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated industries, including pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.