Description

Litorin CAS NO 55749-97-8 is a synthetic peptide analog of bombesin, a neuropeptide with significant biological activity. This compound is a critical research tool for studying receptor binding, signal transduction pathways, and the physiological roles of bombesin-like peptides. It is primarily utilized by researchers and developers in the pharmaceutical and life sciences sectors for preclinical studies, assay development, and as a reference standard in analytical chemistry.

Application

• Biomedical Research: Used as a potent agonist for bombesin receptor subtypes (BB1, BB2, BB3) to investigate their function in cellular signaling, proliferation, and differentiation.
• Pharmacology Studies: Serves as a key reference compound for evaluating the efficacy and binding affinity of novel bombesin receptor antagonists or imaging agents.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays (ELISA, RIA) designed to detect bombesin-related peptides or receptor activity.
• Neuroscience Research: A tool for exploring the role of bombesin-like peptides in the central nervous system, including effects on thermoregulation, satiety, and stress responses.
• Oncology Research: Investigated for its effects on certain cancer cell lines that overexpress bombesin receptors, aiding in targeted therapy research.
• Reference Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories using techniques like HPLC and mass spectrometry.

Basic Information

Product Name	Litorin
CAS No.	55749-97-8
Molecular Formula	C57H83N17O13S
Molecular Weight	1214.4 g/mol
Synonyms	Litorin; [D-Phe12,Leu14]Bombesin; Bombesin (6-14), D-Phe12-Leu14-; Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2; Litorin Peptide; GRP (18-27), D-Phe12-Leu14-; Neuromedin C agonist
EINECS	Contact for details

Quality Control

Our Litorin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. We provide Certificates of Analysis (COA) with detailed batch-specific results for traceability and compliance. Specifications are aligned with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This hygroscopic (moisture-sensitive) material should be allowed to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake. For optimal performance, aliquot contents to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.