Description

S-Adenosyl-5'-L-Methioninesulfate,p-Toluenesulfonate is a high-purity, stabilized salt form of the critical biological cofactor S-adenosylmethionine (SAMe). This compound is essential for research and manufacturing in life sciences due to its role as the primary methyl group donor in numerous enzymatic reactions. It is a vital raw material for pharmaceutical development, biochemical research, and the production of diagnostic reagents.

Application

• Pharmaceutical Intermediates: Key starting material or intermediate in the synthesis of novel therapeutics targeting methylation pathways.
• Biochemical Research: Essential cofactor for in vitro studies of methyltransferases, epigenetics, and cellular metabolism.
• Diagnostic Reagent Manufacturing: Used in the production of enzyme-based assay kits for clinical diagnostics and life science research.
• Nutraceutical & Cosmetic Ingredient: Serves as a high-purity active ingredient for advanced dietary supplements and cosmeceutical formulations.
• Enzyme Catalysis: Employed in biocatalytic processes requiring methyl group transfer for the synthesis of fine chemicals.

Basic Information

Product Name	S-Adenosyl-5'-L-Methioninesulfate,p-Toluenesulfonate
CAS No.	55722-12-8
Molecular Formula	C15H23N6O5S • C7H8O3S
Molecular Weight	766.82 g/mol
Synonyms	S-Adenosyl-L-methionine p-toluenesulfonate sulfate; SAMe tosylate sulfate; AdoMet tosylate sulfate; SAM tosylate sulfate; S-Adenosylmethionine tosylate sulfate; (2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate; p-toluenesulfonate sulfate salt
EINECS	Contact for details

Quality Control

Our S-Adenosyl-5'-L-Methioninesulfate,p-Toluenesulfonate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and cGMP applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed container to reach room temperature before opening to minimize condensation and exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.