Description

n-(n-Acetylglycyl)-L-Valine Butyl Ester is a protected dipeptide derivative, specifically an ester of an acetylated glycyl-valine dipeptide. This compound is a crucial building block in organic synthesis, particularly for the preparation of more complex peptides and peptidomimetics. It is primarily utilized by pharmaceutical research and fine chemical synthesis organizations requiring high-purity intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the solid-phase and solution-phase synthesis of novel therapeutic peptides.
• Peptidomimetic Research: Used to create modified peptide structures with enhanced metabolic stability or bioavailability for drug candidate screening.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Employed in the synthesis of labeled peptides for studying enzyme mechanisms or protein-protein interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	n-(n-Acetylglycyl)-L-Valine Butyl Ester
CAS No.	55712-40-8
Molecular Formula	C13H24N2O4
Molecular Weight	272.34 g/mol
Synonyms	N-Acetylglycyl-L-valine Butyl Ester; N-Ac-Gly-Val-OBu; Ac-Gly-Val-OBu; Butyl N-[(2S)-1-[(2-Acetamidoacetyl)amino]-3-methylbutan-2-yl]carbamate (related IUPAC); Acetyl-glycyl-valine butyl ester; N-Acetyl-glycyl-L-valine butyl ester; Boc-Gly-Val-OtBu (common protected form reference); L-Valine, N-(N-acetylglycyl)-, butyl ester
EINECS	Contact for details

Quality Control

Our n-(n-Acetylglycyl)-L-Valine Butyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.