Description

(R)-N,n-Dimethyl-1-[(S)-2-(Diphenylphosphino)Ferrocenyl]Ethylamine CAS NO 55700-44-2 is a high-value, chiral ferrocenyl phosphine ligand, a cornerstone in asymmetric catalysis. Its significance lies in its ability to induce high enantioselectivity in a variety of transition metal-catalyzed reactions, enabling the production of optically pure intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for synthesizing advanced chiral molecules.

Application

• As a privileged ligand in asymmetric hydrogenation reactions for the synthesis of chiral amino acids, amines, and alcohols.
• As a catalyst component in asymmetric C-C bond-forming reactions, including cross-coupling and allylic substitution.
• For the development of pharmaceutical intermediates requiring high enantiomeric purity, such as active pharmaceutical ingredients (APIs).
• In academic and industrial R&D for exploring new catalytic methodologies and optimizing existing synthetic routes.
• For the synthesis of agrochemicals and other specialty chemicals where chirality impacts biological activity.
• As a key reagent in process chemistry for scaling up enantioselective transformations.

Basic Information

Product Name	(R)-N,n-Dimethyl-1-[(S)-2-(Diphenylphosphino)Ferrocenyl]Ethylamine
CAS No.	55700-44-2
Molecular Formula	C26H28FeNP
Molecular Weight	441.33 g/mol
Synonyms	(R)-N,N-Dimethyl-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethylamine; (R)-(S)-PPFA; (R)-(S)-N,N-Dimethyl-1-[2-(diphenylphosphino)ferrocenyl]ethylamine; (R)-(S)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldimethylamine; Josiphos ligand SL-J009-1; PPFA ligand; Ferrocenylphosphine ligand; Chiral ferrocene ligand
EINECS	Contact for details

Quality Control

Every batch of our (R)-N,n-Dimethyl-1-[(S)-2-(Diphenylphosphino)Ferrocenyl]Ethylamine is synthesized and purified under stringent conditions to ensure exceptional chemical and chiral purity. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be flushed with inert gas after each opening to maintain stability and shelf life.

Specification

Item	Specification
Appearance	Orange to red crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.