Description

1,1,1-Trifluoro-4-(4-Fluorophenyl)-4-Mercapto-3-Buten-2-One is a high-value, multi-functional fluorinated organic intermediate characterized by its unique trifluoromethyl and thiol groups. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceuticals and agrochemicals, where its fluorine atoms impart desirable metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine content enhances efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Employed to introduce fluorinated and thiol-functional side chains into polymers, altering surface properties, chemical resistance, and adhesion.
• Cross-coupling Reactions: The thiol and ketone functionalities make it a valuable substrate in palladium-catalyzed cross-coupling reactions for constructing complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial R&D labs as a versatile fluorinated building block for exploring new synthetic methodologies and material properties.

Basic Information

Product Name	1,1,1-Trifluoro-4-(4-Fluorophenyl)-4-Mercapto-3-Buten-2-One
CAS No.	55674-01-6
Molecular Formula	C10H6F4OS
Molecular Weight	250.21 g/mol
Synonyms	4,4,4-Trifluoro-1-(4-fluorophenyl)-3-mercaptobut-2-en-1-one; 1-(4-Fluorophenyl)-4,4,4-trifluoro-3-mercapto-3-buten-2-one; 4-(4-Fluorophenyl)-4-mercapto-1,1,1-trifluoro-3-buten-2-one; 3-Buten-2-one, 1,1,1-trifluoro-4-(4-fluorophenyl)-4-mercapto-; TFMPMB; 4-Fluorophenyl trifluoromethyl mercapto butenone
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-4-(4-Fluorophenyl)-4-Mercapto-3-Buten-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.