Description

(S)-N,n-Dimethyl-1-[(R)-2-(Diphenylphosphino)Ferrocenyl]Ethylamine CAS NO 55650-58-3 is a high-value, chiral ferrocenyl phosphine ligand, also known as a Josiphos-type ligand. This compound is critically important for its exceptional ability to induce high enantioselectivity in asymmetric catalytic reactions, enabling the production of single-enantiomer intermediates and active pharmaceutical ingredients (APIs). It is primarily needed by manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for advanced synthesis processes such as asymmetric hydrogenation, cross-coupling, and hydroformylation.

Application

• Asymmetric Hydrogenation Catalyst Ligand: For the enantioselective synthesis of chiral amino acids, amines, alcohols, and other pharmaceutical intermediates.
• Pharmaceutical Intermediate Synthesis: Key chiral auxiliary in the production of high-value, single-enantiomer Active Pharmaceutical Ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables asymmetric C-C and C-X bond-forming reactions for complex molecule construction.
• Academic & Industrial R&D: A benchmark ligand for developing and optimizing new catalytic processes in research laboratories.
• Transition Metal Catalyst Preparation: Forms active complexes with rhodium, ruthenium, iridium, and palladium for homogeneous catalysis.

Basic Information

Item	Details
Product Name	(S)-N,n-Dimethyl-1-[(R)-2-(Diphenylphosphino)Ferrocenyl]Ethylamine
CAS No.	55650-58-3
Molecular Formula	C26H28FeNP
Molecular Weight	441.33 g/mol
Synonyms	(R)-(S)-Josiphos; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldimethylamine; (R,S)-PPF-P(CH3)2; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyl dimethylamine; Josiphos SL-J009-1; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldimethylamine; (S,R)-Josiphos; PPF-P(CH3)2
EINECS	Contact for details

Quality Control

Our (S)-N,n-Dimethyl-1-[(R)-2-(Diphenylphosphino)Ferrocenyl]Ethylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes rigorous analytical testing, including HPLC for chemical and chiral purity, NMR for structural confirmation, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.