Description

2-Fluoro-2-Phenylethan-1-Amine is a versatile fluorinated amine building block of significant interest in advanced organic synthesis. Its value lies in the strategic incorporation of both a fluorine atom and a primary amine group onto a phenethyl scaffold, enabling precise modulation of molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, including potential CNS-active compounds and enzyme inhibitors.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom can enhance bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, crucial for producing enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic frameworks that require fluorinated aromatic amines.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of bioactive molecules to study metabolic pathways and receptor interactions.
• Custom Synthesis Building Block: Provides a flexible starting point for contract research organizations (CROs) and fine chemical companies engaged in bespoke molecular synthesis.

Basic Information

Product Name	2-Fluoro-2-Phenylethan-1-Amine
CAS No.	55601-20-2
Molecular Formula	C8H10FN
Molecular Weight	139.17 g/mol
Synonyms	2-Fluoro-2-phenylethylamine; α-Fluorophenethylamine; 1-Amino-2-fluoro-2-phenylethane; (2-Fluoro-2-phenylethyl)amine; 2-Fluoro-1-phenylethanamine; 2-Fluoro-β-phenylethylamine; Benzenemethanamine, α-fluoro-; 55601-20-2
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-2-Phenylethan-1-Amine is produced and analyzed under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by advanced analytical techniques, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.