Description

3,3,3-Trifluoro-2-Aminoisobutyrate is a specialized fluorinated amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its ability to introduce the metabolically stable trifluoromethyl group and a chiral amino acid backbone into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Peptidomimetics & Bioactive Compounds: Serves as a non-natural amino acid analog for constructing modified peptides and peptidomimetics with improved metabolic resistance and binding affinity.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty chemicals where unique surface properties or chemical resistance are required.
• Chemical Biology Probes: Utilized as a building block for labeled compounds and probes used in biochemical and pharmacological research studies.

Basic Information

Product Name	3,3,3-Trifluoro-2-Aminoisobutyrate
CAS No.	55601-02-0
Molecular Formula	C5H6F3NO2
Molecular Weight	157.10 g/mol
Synonyms	2-Amino-3,3,3-trifluoroisobutyric acid; 3,3,3-Trifluoro-DL-2-aminoisobutyric acid; 3,3,3-Trifluoro-2-aminoisobutyric acid; DL-3,3,3-Trifluoro-2-aminoisobutyric acid; 2-Amino-3,3,3-trifluoro-2-methylpropanoic acid; TF-Aib; Trifluoroisobutyric acid, 2-amino-; α-Amino-β,β,β-trifluoroisobutyric acid
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoro-2-Aminoisobutyrate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.