Description

(+)-Butaclamol Hydrochloride CAS NO 55528-07-9 is a high-purity, enantiomerically pure chemical compound of significant interest in neuropharmacological research. It serves as a potent and selective dopamine receptor antagonist, making it a critical reference standard and research tool. This product is essential for pharmaceutical R&D laboratories, academic institutions, and analytical facilities focused on neuroscience, receptor binding studies, and the development of central nervous system (CNS) therapeutics.

Application

• Pharmacological Research: Used as a potent and selective antagonist in dopamine D1 and D2 receptor binding assays and functional studies.
• Neuroscience Studies: A key tool for investigating dopaminergic pathways, neurotransmission, and behaviors associated with dopamine signaling.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and lead optimization programs targeting CNS disorders such as schizophrenia and Parkinson's disease.
• Biochemical Assays: Utilized in vitro to study receptor-ligand interactions, signal transduction mechanisms, and enzyme inhibition related to dopaminergic systems.
• Academic & Clinical Research: Supports fundamental research in universities and hospitals exploring the neurochemical basis of mental health and neurological conditions.

Basic Information

Item	Details
Product Name	(+)-Butaclamol Hydrochloride
CAS No.	55528-07-9
Molecular Formula	C25H31NO.HCl
Molecular Weight	397.98 g/mol
Synonyms	(+)-Butaclamol HCl; Dexbutaclamol Hydrochloride; (3aS,13bR)-2,3,3a,4,5,13b-Hexahydro-1H-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinolin-3a-ol Hydrochloride; NSC 339024; Butaclamol Hydrochloride (+)-isomer; FBA 1653; AY-23,028
EINECS	Contact for details

Quality Control

Our (+)-Butaclamol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, identity confirmation by spectroscopic methods, and stringent control of impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all test results against established specifications. Our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (enantiomeric excess)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.